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Registros recuperados: 10
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Cytokine accumulation in osteitis fibrosa of renal osteodystrophy BJMBR
Duarte,M.E.L.; Carvalho,E.F.; Cruz,E.A.S.; Lucena,S.B.G.; Andress,D.L..
Bone marrow fibrosis occurs in association with a number of pathological states. Despite the extensive fibrosis that sometimes characterizes renal osteodystrophy, little is known about the factors that contribute to marrow accumulation of fibrous tissue. Because circulating cytokines are elevated in uremia, possibly in response to elevated parathyroid hormone levels, we have examined bone biopsies from 21 patients with end-stage renal disease and secondary hyperparathyroidism. Bone sections were stained with antibodies to human interleukin-1alpha (IL-1alpha), IL-6, IL-11, tumor necrosis factor-alpha (TNF-alpha) and transforming growth factor-ß (TGF-ß) using an undecalcified plastic embedding method. Intense staining for IL-1alpha, IL-6, TNF-alpha and TGF-ß...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cytokines; Osteitis fibrosa; Renal osteodystrophy; Chronic renal failure; Dialysis; Secondary hyperparathyroidism.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000100004
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Determination of renal function in long-term heart transplant patients by measurement of urinary retinol-binding protein levels BJMBR
Chinen,R.; Câmara,N.O.S.; Nishida,S.; Silva,M.S.; Rodrigues,D.A.; Pereira,A.B.; Pacheco-Silva,A..
Significant improvements have been noted in heart transplantation with the advent of cyclosporine. However, cyclosporine use is associated with significant side effects, such as chronic renal failure. We were interested in evaluating the incidence of long-term renal dysfunction in heart transplant recipients. Fifty-three heart transplant recipients were enrolled in the study. Forty-three patients completed the entire evaluation and follow-up. Glomerular (serum creatinine, creatinine clearance measured, and creatinine clearance calculated) and tubular functions (urinary retinol-binding protein, uRBP) were re-analyzed after 18 months. At the enrollment time, the prevalence of renal failure ranged from 37.7 to 54% according to criteria used to define it...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Renal function; Urinary retinol-binding protein; Heart transplant; Graft survival; Chronic renal failure.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006001000006
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Dialysis, time and death: comparisons of two consecutive decades among patients treated at the same Brazilian dialysis center BJMBR
De-Lima,J.J.G.; da-Fonseca,J.A.; Godoy,A.D..
The survival of hemodialysis patients is likely to be influenced not only by well-known risk factors like age and comorbidity, but also by changes in dialysis technology and practices accumulated along time. We compared the survival curves, dialysis routines and some risk factors of two groups of patients admitted to a Brazilian maintenance hemodialysis program during two consecutive decades: March 1977 to December 1986 (group 1, N = 162) and January 1987 to June 1997 (group 2, N = 237). The median treatment time was 22 months (range 1-198). Survival curves were constructed using the Kaplan-Meier method and compared using the log-rank method. The Cox proportional hazard regression model was used to investigate the more important variables associated with...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Chronic renal failure; Hemodialysis; Kaplan-Meier survival curves; Risk factors.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000300007
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Effect of castration on renal glycosaminoglycans and their urinary excretion in male and female rats with chronic renal failure BJMBR
Lemos,C.C.S.; Tovar,A.M.F.; Guimarães,M.A.M.; Bregman,R..
Glycosaminoglycans (GAGs) participate in a variety of processes in the kidney, and evidence suggests that gender-related hormones participate in renal function. The aim of this study was to analyze the relationship of GAGs, gender, and proteinuria in male and female rats with chronic renal failure (CRF). GAGs were analyzed in total kidney tissue and 24-h urine of castrated (c), male (M), and female (F) Wistar control (C) rats (CM, CMc, CF, CFc) and after 30 days of CRF induced by 5/6 nephrectomy (CRFM, CRFMc, CRFF, CRFFc). Total GAG quantification and composition were determined using agarose and polyacrylamide gel electrophoresis, respectively. Renal GAGs were higher in CF compared to CM. CRFM presented an increase in renal GAGs, heparan sulfate (HS), and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Castration; Chronic renal failure; Gender; Glycosaminoglycans; Proteinuria.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000700567
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End-stage renal disease due to delayed diagnosis of renal tuberculosis: a fatal case report BJID
Daher,Elizabeth De Francesco; Silva Júnior,Geraldo Bezerra da; Damasceno,Renata Trindade; Santos,Gustavo Martins dos; Corsino,Germana Alves; Silva,Sônia Leite da; Gutiérrez-Adrianzén,Oswaldo Augusto.
Renal TB is difficult to diagnose, because many patients present themselves with lower urinary symptoms which are typical of bacterial cystitis. We report a case of a young woman with renal TB and ESRD. She was admitted with complaints of adynamia, anorexia, fever, weight loss, dysuria and generalized edema for 10 months. At physical examination she was febrile (39ºC), and her abdomen had increased volume and was painful at palpation. Laboratorial tests showed serum urea=220mg/dL, creatinine=6.6mg/dL, hemoglobin=7.9g/dL, hematocrit=24.3%, leukocytes=33,600/mm³ and platelets=664,000/mm³. Urinalysis showed an acid urine (pH=5.0), leukocyturia (2+/4+) and mild proteinuria (1+/4+). She was also oliguric (urinary volume <400mL/day). Abdominal echography...
Tipo: Info:eu-repo/semantics/report Palavras-chave: Tuberculosis; Renal tuberculosis; Extrapulmonary tuberculosis; End-stage renal disease; Chronic renal failure.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000100036
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Factors associated with the development of renal complications of diabetes mellitus in São Paulo city BJMBR
The incidence of diabetic end-stage renal failure (ESRF) varies worldwide and risk factors have been demonstrated in several populations. The objective of the present study was to identify possible factors associated with the risk of development of ESRF in patients with diabetes mellitus (DM). Two groups of diabetic subjects were included in a case-control study: 1) one group was submitted to renal replacement therapies, attending dialysis centers in São Paulo city and 2) the same number of controls without clinical nephropathy (two negative dipstick tests for urine protein), matched for duration of DM, were obtained from an outpatient clinic. A standardized questionnaire was used by a single investigator and additional data were obtained from the medical...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Chronic renal failure; Diabetes mellitus; Diabetic nephropathy; Associated factors.
Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000600006
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Nutritional status of hemodialysis patients with secondary hyperparathyroidism BJMBR
Rezende,L.T.T.; Cuppari,L.; Carvalho,A.B.; Canziani,M.E.F.; Manfredi,S.R.; Cendoroglo,M.; Sigulem,D.M.; Draibe,S.A..
The repercussions of secondary hyperparathyroidism on the nutritional status of chronic renal failure patients have not been well established. Therefore, the aim of this study was to compare the nutritional indices of hemodialysis patients with and without secondary hyperparathyroidism. Sixteen hemodialysis patients with serum parathyroid hormone (PTH) levels higher than 420 pg/ml (hyperparathyroidism group) were matched for gender, age and length of dialysis treatment to 16 patients with serum PTH between 64 and 290 pg/ml (control group). The following parameters were assessed: anthropometric indices (body mass index, skinfold thickness, midarm muscle circumference and body fat), 4-day food diaries, protein catabolic rate, biochemical indices (blood urea...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nutritional assessment; Parathormone; Chronic renal failure; Secondary hyperparathyroidism.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000001100007
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Periodontal disease characterization in dogs with normal renal function or chronic renal failure Ciência Rural
Barbudo-Selmi,Glenda Ramalho; Carvalho,Marileda Bonafim; Selmi,André Luis; Martins,Silvio Emílio Cuevas.
The purpose of this study was to evaluate periodontal disease (PD) in dogs with chronic renal failure (CRF) and to compare it to PD in dogs with normal renal function (NRF). Twelve dogs with CRF and 24 dogs with NRF, all presenting dental pocket formation, were compared. In all dogs, serum creatinine, blood urea nitrogen, urine specific gravity and total red and white blood cells were determined. A complete oral examination was also performed including evaluation of bacterial plaque, gingivitis, gingival recession, pocket, calculus, dental mobility, dental loss, and ulcers. These data were used to calculate plaque index (PI), gingival index (GI) and periodontal destruction index (PDI). PD was graded as mild, moderate or severe based on the results. Mild,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Periodontal disease; Chronic renal failure; Dogs.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782004000100017
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Prognostic effect of high-flux hemodialysis in patients with chronic kidney disease BJMBR
Li,X.; Xu,H.; Xiao,X.C.; Deng,S.L.; Wang,W.; Tang,R..
We investigated the prognostic effects of high-flux hemodialysis (HFHD) and low-flux hemodialysis (LFHD) in patients with chronic kidney disease (CKD). Both an electronic and a manual search were performed based on our rigorous inclusion and exclusion criteria to retrieve high-quality, relevant clinical studies from various scientific literature databases. Comprehensive meta-analysis 2.0 (CMA 2.0) was used for the quantitative analysis. We initially retrieved 227 studies from the database search. Following a multi-step screening process, eight high-quality studies were selected for our meta-analysis. These eight studies included 4967 patients with CKD (2416 patients in the HFHD group, 2551 patients in the LFHD group). The results of our meta-analysis...
Tipo: Info:eu-repo/semantics/article Palavras-chave: High-flux hemodialysis; Low-flux hemodialysis; Chronic kidney disease; Chronic renal failure; All-cause death rate; Cardiovascular death rate.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000100706
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Vancomycin: the need to suit serum concentrations in hemodialysis patients BJID
Marengo,Lívia Luize; Del Fiol,Fernando de Sá; Oliveira,Sara de Jesus; Nakagawa,Celso; Croco,Eduardo Leite; Barberato-Filho,Silvio; Peçanha,Marcela Pellegrini; Silva,Douglas Felix da; Toledo,Maria Inês de.
The vancomycin dose for hemodialysis (HD) patients should be adjusted by monitoring drug serum concentrations. However, this procedure is not available in most health services in Brazil, which usually adopts protocols based on published studies. The trials available are controversial, and several have not been conducted with current dialyzers. This study aimed at assessing the suitability of vancomycin serum concentrations in HD patients at a public hospital. Blood samples of HD patients were collected from November 2006 to May 2007, at time intervals of 48, 96, 120, or 168 hours after vancomycin administration. Drug measurement was performed with polarized light immunofluorescence. Approximately 86% of trough vancomycin serum concentrations were below the...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Vancomycin; Chronic renal failure; Hemodialysis.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000200019
Registros recuperados: 10
Primeira ... 1 ... Última
 

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